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Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics
The Fanconi Anemia (FA) pathway consists of proteins involved in repairing DNA damage, including interstrand cross-links (ICLs). The pathway contains an upstream multiprotein core complex that mediates the monoubiquitylation of the FANCD2 and FANCI heterodimer, and a downstream pathway that converge...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368156/ https://ncbi.nlm.nih.gov/pubmed/22693661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/481583 |
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