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Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

BACKGROUND: The Fanconi anemia (FA) pathway is a multigene DNA damage response network implicated in the repair of DNA lesions that arise during replication or after exogenous DNA damage. The FA pathway displays synthetic lethal relationship with certain DNA repair genes such as ATM (Ataxia Telangec...

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書誌詳細
主要な著者: Landais, Igor, Hiddingh, Sanne, McCarroll, Matthew, Yang, Chao, Sun, Aiming, Turker, Mitchell S, Snyder, James P, Hoatlin, Maureen E
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807854/
https://ncbi.nlm.nih.gov/pubmed/20043851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-133
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