Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

BACKGROUND: The Fanconi anemia (FA) pathway is a multigene DNA damage response network implicated in the repair of DNA lesions that arise during replication or after exogenous DNA damage. The FA pathway displays synthetic lethal relationship with certain DNA repair genes such as ATM (Ataxia Telangec...

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Bibliographische Detailangaben
Hauptverfasser: Landais, Igor, Hiddingh, Sanne, McCarroll, Matthew, Yang, Chao, Sun, Aiming, Turker, Mitchell S, Snyder, James P, Hoatlin, Maureen E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807854/
https://ncbi.nlm.nih.gov/pubmed/20043851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-133
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