Effects of Restrained Sampling Space and Nonplanar Amino Groups on Free-Energy Predictions for RNA with Imino and Sheared Tandem GA Base Pairs Flanked by GC, CG, iGiC or iCiG Base Pairs

Guanine-adenine (GA) base pairs play important roles in determining the structure, dynamics, and stability of RNA. In RNA internal loops, GA base pairs often occur in tandem arrangements and their structure is context and sequence dependent. Calculations reported here test the thermodynamic integrat...

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Autors principals: Yildirim, Ilyas, Stern, Harry A., Sponer, Jiri, Spackova, Nada, Turner, Douglas H.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2009
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807739/
https://ncbi.nlm.nih.gov/pubmed/20090924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct800540c
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