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Effects of Restrained Sampling Space and Nonplanar Amino Groups on Free-Energy Predictions for RNA with Imino and Sheared Tandem GA Base Pairs Flanked by GC, CG, iGiC or iCiG Base Pairs
Guanine-adenine (GA) base pairs play important roles in determining the structure, dynamics, and stability of RNA. In RNA internal loops, GA base pairs often occur in tandem arrangements and their structure is context and sequence dependent. Calculations reported here test the thermodynamic integrat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2009
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807739/ https://ncbi.nlm.nih.gov/pubmed/20090924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct800540c |
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