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Is, indeed, the prion protein a Harlequin servant of “many” masters?

Tens of putative interacting partners of the cellular prion protein (PrP(C)) have been identified, yet the physiologic role of PrP(C) remains unclear. For the first time, however, a recent paper has demonstrated that the absence of PrP(C) produces a lethal phenotype. Starting from this evidence, her...

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Bibliographic Details
Main Authors: Sorgato, M Catia, Peggion, Caterina, Bertoli, Alessandro
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807692/
https://ncbi.nlm.nih.gov/pubmed/19887913
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