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Is, indeed, the prion protein a Harlequin servant of “many” masters?

Tens of putative interacting partners of the cellular prion protein (PrP(C)) have been identified, yet the physiologic role of PrP(C) remains unclear. For the first time, however, a recent paper has demonstrated that the absence of PrP(C) produces a lethal phenotype. Starting from this evidence, her...

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Bibliografske podrobnosti
Main Authors: Sorgato, M Catia, Peggion, Caterina, Bertoli, Alessandro
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807692/
https://ncbi.nlm.nih.gov/pubmed/19887913
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