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The Link of the Prion Protein with Ca(2+) Metabolism and ROS Production, and the Possible Implication in Aβ Toxicity

The cellular prion protein (PrP(C)) is an ubiquitous cell surface protein mostly expressed in neurons, where it localizes to both pre- and post-synaptic membranes. PrP(C) aberrant conformers are the major components of mammalian prions, the infectious agents responsible for incurable neurodegenerati...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Mol Sci
मुख्य लेखकों: De Mario, Agnese, Peggion, Caterina, Massimino, Maria Lina, Norante, Rosa Pia, Zulian, Alessandra, Bertoli, Alessandro, Sorgato, Maria Catia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770541/
https://ncbi.nlm.nih.gov/pubmed/31546771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184640
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