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The Link of the Prion Protein with Ca(2+) Metabolism and ROS Production, and the Possible Implication in Aβ Toxicity
The cellular prion protein (PrP(C)) is an ubiquitous cell surface protein mostly expressed in neurons, where it localizes to both pre- and post-synaptic membranes. PrP(C) aberrant conformers are the major components of mammalian prions, the infectious agents responsible for incurable neurodegenerati...
Sparad:
| I publikationen: | Int J Mol Sci |
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| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
MDPI
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6770541/ https://ncbi.nlm.nih.gov/pubmed/31546771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184640 |
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