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The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase
The prion protein (PrP(C)) is a cell surface glycoprotein mainly expressed in neurons, whose misfolded isoforms generate the prion responsible for incurable neurodegenerative disorders. Whereas PrP(C) involvement in prion propagation is well established, PrP(C) physiological function is still enigma...
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Publicado no: | Front Cell Neurosci |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623396/ https://ncbi.nlm.nih.gov/pubmed/26578881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00416 |
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