The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase

The prion protein (PrP(C)) is a cell surface glycoprotein mainly expressed in neurons, whose misfolded isoforms generate the prion responsible for incurable neurodegenerative disorders. Whereas PrP(C) involvement in prion propagation is well established, PrP(C) physiological function is still enigma...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Cell Neurosci
Päätekijät: De Mario, Agnese, Castellani, Angela, Peggion, Caterina, Massimino, Maria Lina, Lim, Dmitry, Hill, Andrew F., Sorgato, M. Catia, Bertoli, Alessandro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2015
Aiheet:
Neuroscience
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623396/
https://ncbi.nlm.nih.gov/pubmed/26578881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00416
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