The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase

The prion protein (PrP(C)) is a cell surface glycoprotein mainly expressed in neurons, whose misfolded isoforms generate the prion responsible for incurable neurodegenerative disorders. Whereas PrP(C) involvement in prion propagation is well established, PrP(C) physiological function is still enigma...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Neurosci
Hoofdauteurs: De Mario, Agnese, Castellani, Angela, Peggion, Caterina, Massimino, Maria Lina, Lim, Dmitry, Hill, Andrew F., Sorgato, M. Catia, Bertoli, Alessandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623396/
https://ncbi.nlm.nih.gov/pubmed/26578881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00416
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