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Alcohol Dehydrogenase Accentuates Ethanol-Induced Myocardial Dysfunction and Mitochondrial Damage in Mice: Role of Mitochondrial Death Pathway

OBJECTIVES: Binge drinking and alcohol toxicity are often associated with myocardial dysfunction possibly due to accumulation of the ethanol metabolite acetaldehyde although the underlying mechanism is unknown. This study was designed to examine the impact of accelerated ethanol metabolism on myocar...

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Библиографические подробности
Главные авторы: Guo, Rui, Ren, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807457/
https://ncbi.nlm.nih.gov/pubmed/20090911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008757
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