Aldehyde Dehydrogenase 2 Knockout Accentuates Ethanol-Induced Cardiac Depression: Role of Protein Phosphatases

Alcohol consumption leads to myocardial contractile dysfunction possibly due to the toxicity of ethanol and its major metabolite acetaldehyde. This study was designed to examine the influence of mitochondrial aldehyde dehydrogenase-2 (ALDH2) knockout (KO) on acute ethanol exposure-induced cardiomyoc...

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Detalhes bibliográficos
Main Authors: Ma, Heng, Byra, Emily A., Yu, Lu, Hu, Nan, Kitagawa, Kyoko, Nakayama, Keiichi I., Kawamoto, Toshihiro, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885537/
https://ncbi.nlm.nih.gov/pubmed/20362583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.03.017
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