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Alcohol Dehydrogenase Accentuates Ethanol-Induced Myocardial Dysfunction and Mitochondrial Damage in Mice: Role of Mitochondrial Death Pathway

OBJECTIVES: Binge drinking and alcohol toxicity are often associated with myocardial dysfunction possibly due to accumulation of the ethanol metabolite acetaldehyde although the underlying mechanism is unknown. This study was designed to examine the impact of accelerated ethanol metabolism on myocar...

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Detalhes bibliográficos
Main Authors: Guo, Rui, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807457/
https://ncbi.nlm.nih.gov/pubmed/20090911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008757
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