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Cardiac Overexpression of Alcohol Dehydrogenase Exacerbates Chronic Ethanol Ingestion-Induced Myocardial Dysfunction and Hypertrophy: Role of Insulin Signaling and ER stress
Chronic alcohol intake leads to alcoholic cardiomyopathy characterized by cardiac hypertrophy and contractile dysfunction possibly related to the toxicity of the ethanol metabolite acetaldehyde. This study examined the impact of augmented acetaldehyde exposure on myocardial function, geometry, and i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2501109/ https://ncbi.nlm.nih.gov/pubmed/18377926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.02.276 |
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