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DNA Plasticity Is a Key Determinant of the Energetics of Binding of Jun-Fos Heterodimeric Transcription Factor to Genetic Variants of TGACGTCA Motif

The Jun-Fos heterodimeric transcription factor is a target of a diverse array of signaling cascades that initiate at the cell surface and converge in the nucleus and ultimately result in the expression of genes involved in a multitude of cellular processes central to health and disease. Here, using...

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Detalhes bibliográficos
Main Authors: Seldeen, Kenneth L., McDonald, Caleb B., Deegan, Brian J., Bhat, Vikas, Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807364/
https://ncbi.nlm.nih.gov/pubmed/19921846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901392k
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