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A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation
Neuronal differentiation is regulated by proneural genes that promote neurogenesis and inhibitory mechanisms that maintain progenitors. This raises the question of how the up-regulation of proneural genes required to initiate neurogenesis occurs in the presence of such inhibition. We carried out los...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807355/ https://ncbi.nlm.nih.gov/pubmed/20080956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.554510 |
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