Astrocytic trans-differentiation completes a multicellular paracrine feedback loop required for medulloblastoma tumor growth

The tumor microenvironment (TME) is critical for tumor progression. However, the establishment and function of TME remain obscure due to its complex cellular composition. Using a mouse genetic system called Mosaic Analysis with Double Markers (MADM), we delineated TME evolution at single-cell resolu...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Yao, Maojin, Ventura, P. Britten, Jiang, Ying, Rodriguez, Fausto J., Wang, Lixin, Perry, Justin S. A., Yang, Yibo, Wahl, Kelsey, Crittenden, Rowena B., Bennett, Mariko L., Qi, Lin, Gong, Cong-Cong, Li, Xiao-Nan, Barres, Ben A., Bender, Timothy P., Ravichandran, Kodi S., Janes, Kevin A., Eberhart, Charles G., Zong, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259679/
https://ncbi.nlm.nih.gov/pubmed/31983537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.024
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