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A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation
Neuronal differentiation is regulated by proneural genes that promote neurogenesis and inhibitory mechanisms that maintain progenitors. This raises the question of how the up-regulation of proneural genes required to initiate neurogenesis occurs in the presence of such inhibition. We carried out los...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807355/ https://ncbi.nlm.nih.gov/pubmed/20080956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.554510 |
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