Inducible Priming Phosphorylation Promotes Ligand-independent Degradation of the IFNAR1 Chain of Type I Interferon Receptor

Phosphorylation-dependent ubiquitination and ensuing down-regulation and lysosomal degradation of the interferon α/β receptor chain 1 (IFNAR1) of the receptor for Type I interferons play important roles in limiting the cellular responses to these cytokines. These events could be stimulated either by...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Bhattacharya, Sabyasachi, HuangFu, Wei-Chun, Liu, Jianghuai, Veeranki, Sudhakar, Baker, Darren P., Koumenis, Constantinos, Diehl, J. Alan, Fuchs, Serge Y.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Mechanisms of Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807289/
https://ncbi.nlm.nih.gov/pubmed/19948722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071498
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars