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Cluster Analysis of Insulin Action in Adipocytes Reveals a Key Role for Akt at the Plasma Membrane

The phosphatidylinositol 3-kinase/Akt pathway regulates many biological processes, including insulin-regulated GLUT4 insertion into the plasma membrane. However, Akt operates well below its capacity to facilitate maximal GLUT4 translocation. Thus, reconciling modest changes in Akt expression or acti...

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Autors principals: Ng, Yvonne, Ramm, Georg, Burchfield, James G., Coster, Adelle C. F., Stöckli, Jacqueline, James, David E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807282/
https://ncbi.nlm.nih.gov/pubmed/19897488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060236
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