DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences

DNA methylation might have a significant role in preventing normal differentiation in pediatric cancers. We used a genomewide method for detecting regions of CpG methylation on the basis of the increased melting temperature of methylated DNA, termed denaturation analysis of methylation differences (...

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Bibliographic Details
Main Authors: Diede, Scott J., Guenthoer, Jamie, Geng, Linda N., Mahoney, Sarah E., Marotta, Michael, Olson, James M., Tanaka, Hisashi, Tapscott, Stephen J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806770/
https://ncbi.nlm.nih.gov/pubmed/19966297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907606106
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