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Genome-wide DNA methylation studies suggest distinct DNA methylation patterns in pediatric embryonal and alveolar rhabdomyosarcomas

Rhabdomyosarcoma is the most common soft-tissue sarcoma in children. While cytogenetic abnormalities have been well characterized in this disease, aberrant epigenetic events such as DNA hypermethylation have not been described in genome-wide studies. We have analyzed the methylation status of 25,500...

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Detalhes bibliográficos
Main Authors: Mahoney, Sarah E., Yao, Zizhen, Keyes, C. Chip, Tapscott, Stephen J., Diede, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368822/
https://ncbi.nlm.nih.gov/pubmed/22419069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19463
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