Assessment of palindromes as platforms for DNA amplification in breast cancer

DNA amplification, particularly of chromosomes 8 and 11, occurs frequently in breast cancer and is a key factor in tumorigenesis, often associated with poor prognosis. The mechanisms involved in the amplification of these regions are not fully understood. Studies from model systems have demonstrated...

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Bibliografske podrobnosti
Main Authors: Guenthoer, Jamie, Diede, Scott J., Tanaka, Hisashi, Chai, Xiaoyu, Hsu, Li, Tapscott, Stephen J., Porter, Peggy L.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266031/
https://ncbi.nlm.nih.gov/pubmed/21752925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.117226.110
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