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Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors
Oncogene amplification confers a growth advantage to tumor cells for clonal expansion. There are several, recurrently amplified oncogenes throughout the human genome. However, it remains unclear whether this recurrent amplification is solely a manifestation of increased fitness resulting from random...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314454/ https://ncbi.nlm.nih.gov/pubmed/28211519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41921 |
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