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Intrastrand Annealing Leads to the Formation of a Large DNA Palindrome and Determines the Boundaries of Genomic Amplification in Human Cancer

Amplification of large chromosomal regions (gene amplification) is a common somatic alteration in human cancer cells and often is associated with advanced disease. A critical event initiating gene amplification is a DNA double-strand break (DSB), which is immediately followed by the formation of a l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanaka, Hisashi, Cao, Yi, Bergstrom, Donald A., Kooperberg, Charles, Tapscott, Stephen J., Yao, Meng-Chao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820508/
https://ncbi.nlm.nih.gov/pubmed/17242211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01313-06
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