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Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

We previously reported that some of the rare broadly reactive, HIV-1 neutralizing antibodies are polyreactive, leading to the hypothesis that induction of these types of neutralizing antibody may be limited by immunologic tolerance. However, the notion that such antibodies are sufficiently autoreact...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Verkoczy, Laurent, Diaz, Marilyn, Holl, T. Matt, Ouyang, Ying-Bin, Bouton-Verville, Hilary, Alam, S. Munir, Liao, Hua-Xin, Kelsoe, Garnett, Haynes, Barton F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806760/
https://ncbi.nlm.nih.gov/pubmed/20018688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912914107
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