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The activation mechanism of α(1)β(2)γ(2S) and α(3)β(3)γ(2S) GABA(A) receptors

The α(1)β(2)γ(2) and α(3)β(3)γ(2) are two isoforms of γ-aminobutyric acid type A (GABA(A)) receptor that are widely distributed in the brain. Both are found at synapses, for example in the thalamus, where they mediate distinctly different inhibitory postsynaptic current profiles, particularly with r...

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Detalhes bibliográficos
Main Authors: Keramidas, Angelo, Harrison, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806416/
https://ncbi.nlm.nih.gov/pubmed/20038526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910317
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