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Regulation of Akt(ser473) phosphorylation by Choline kinase in breast carcinoma cells

BACKGROUND: The serine/threonine kinase PKB/Akt plays essential role in various cellular processes including cell growth and proliferation, metabolism and cell survival. The importance of the Akt pathway is highlighted by the mutation of various components of the pathway such as the PTEN and PI3-kin...

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Main Authors: Chua, Boon Tin, Gallego-Ortega, David, de Molina, Ana Ramirez, Ullrich, Axel, Lacal, Juan Carlos, Downward, Julian
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806310/
https://ncbi.nlm.nih.gov/pubmed/20042122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-131
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