Regulation of Akt(ser473) phosphorylation by Choline kinase in breast carcinoma cells

BACKGROUND: The serine/threonine kinase PKB/Akt plays essential role in various cellular processes including cell growth and proliferation, metabolism and cell survival. The importance of the Akt pathway is highlighted by the mutation of various components of the pathway such as the PTEN and PI3-kin...

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Hauptverfasser: Chua, Boon Tin, Gallego-Ortega, David, de Molina, Ana Ramirez, Ullrich, Axel, Lacal, Juan Carlos, Downward, Julian
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806310/
https://ncbi.nlm.nih.gov/pubmed/20042122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-131
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