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Quality control by the ribosome following peptide bond formation
The overall fidelity of protein synthesis has been thought to rely on the combined accuracy of two basic processes; the aminoacylation of tRNAs with their cognate amino acid by the aminoacyl-tRNA synthetases and the selection of cognate aminoacyl-tRNAs by the ribosome in cooperation with the GTPase...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805954/ https://ncbi.nlm.nih.gov/pubmed/19092806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07582 |
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