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An anthrax lethal factor mutant that is defective at causing pyroptosis retains pro-apoptotic activity

Anthrax lethal toxin triggers death in some cell types, such as macrophages, and causes a variety of cellular dysfunctions in others. Collectively, these effects dampen the innate and adaptive immune systems to allow Bacillus anthracis to survive and proliferate in the mammalian host. The diverse ef...

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Bibliografske podrobnosti
Main Authors: Ngai, Stephanie, Batty, Sarah, Liao, Kuo-Chieh, Mogridge, Jeremy
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805769/
https://ncbi.nlm.nih.gov/pubmed/19922472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07458.x
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