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Inhibition of Anthrax Lethal Toxin-Induced Cytolysis of RAW264.7 Cells by Celastrol

BACKGROUND: Bacillus anthracis is the bacterium responsible for causing anthrax. The ability of B. anthracis to cause disease is dependent on a secreted virulence factor, lethal toxin, that promotes survival of the bacteria in the host by impairing the immune response. A well-studied effect of letha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chapelsky, Sarah, Batty, Sarah, Frost, Mia, Mogridge, Jeremy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170518/
https://ncbi.nlm.nih.gov/pubmed/18183301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001421
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