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Nucleosomes Are Depleted at the VSG Expression Site Transcribed by RNA Polymerase I in African Trypanosomes

In most eukaryotes, RNA polymerase I (Pol I) exclusively transcribes long arrays of identical rRNA genes (ribosomal DNA [rDNA]). African trypanosomes have the unique property of using Pol I to also transcribe the variant surface glycoprotein VSG genes. VSGs are important virulence factors because th...

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Detalhes bibliográficos
Main Authors: Figueiredo, Luisa M., Cross, George A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805297/
https://ncbi.nlm.nih.gov/pubmed/19915072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00282-09
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