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A Histone Methyltransferase Modulates Antigenic Variation in African Trypanosomes

To evade the host immune system, several pathogens periodically change their cell-surface epitopes. In the African trypanosomes, antigenic variation is achieved by tightly regulating the expression of a multigene family encoding a large repertoire of variant surface glycoproteins (VSGs). Immune evas...

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Hlavní autoři: Figueiredo, Luisa M, Janzen, Christian J, Cross, George A.M
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443197/
https://ncbi.nlm.nih.gov/pubmed/18597556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060161
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