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A novel ISWI is involved in VSG expression site downregulation in African trypanosomes

African trypanosomes show monoallelic expression of one of about 20 telomeric variant surface glycoprotein (VSG) gene-expression sites (ESs) while multiplying in the mammalian bloodstream. We screened for genes involved in ES silencing using flow cytometry and RNA interference (RNAi). We show that a...

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Detalhes bibliográficos
Main Authors: Hughes, Katie, Wand, Matthew, Foulston, Lucy, Young, Rosanna, Harley, Kate, Terry, Stephen, Ersfeld, Klaus, Rudenko, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864976/
https://ncbi.nlm.nih.gov/pubmed/17431399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601678
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