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Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury

Studies in experimental models and controlled patient trials indicate that opioids are effective in managing neuropathic pain. However, side effects secondary to their central nervous system actions present barriers to their clinical use. Therefore, we examined whether activation of the peripheral m...

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Detalhes bibliográficos
Main Authors: Guan, Yun, Johanek, Lisa M., Hartke, Timothy V., Shim, Beom, Tao, Yuan-Xiang, Ringkamp, Matthias, Meyer, Richard A., Raja, Srinivasa N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805197/
https://ncbi.nlm.nih.gov/pubmed/18276075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.01.004
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