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EQUILIBRIUM UNFOLDING OF THE RETINOID X RECEPTOR LIGAND BINDING DOMAIN AND CHARACTERIZATION OF AN UNFOLDING INTERMEDIATE(†*)
The retinoid X receptor (RXR) is a ligand-activated transcription factor that plays an important role in growth and development and the maintenance of cellular homeostasis. A thermodynamic ultraviolet circular dichroism, tryptophan fluorescence and ligand binding activity with guanidine as a chemica...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805030/ https://ncbi.nlm.nih.gov/pubmed/19167149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2008.12.001 |
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