EQUILIBRIUM UNFOLDING OF THE RETINOID X RECEPTOR LIGAND BINDING DOMAIN AND CHARACTERIZATION OF AN UNFOLDING INTERMEDIATE(†*)

The retinoid X receptor (RXR) is a ligand-activated transcription factor that plays an important role in growth and development and the maintenance of cellular homeostasis. A thermodynamic ultraviolet circular dichroism, tryptophan fluorescence and ligand binding activity with guanidine as a chemica...

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Detalhes bibliográficos
Main Authors: Harder, Mark E., Malencik, Dean A., Yan, Xuguang, Broderick, David, Leid, Mark, Anderson, Sonia R., Deinzer, Max L., Schimerlik, Michael I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805030/
https://ncbi.nlm.nih.gov/pubmed/19167149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2008.12.001
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