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TGFβ1 and T(reg) cells: alliance for tolerance
Transforming growth factor β1 (TGFβ1), an important pleiotropic, immunoregulatory cytokine, uses distinct signaling mechanisms in lymphocytes to affect T-cell homeostasis, regulatory T (T(reg))-cell and effector-cell function and tumorigenesis. Defects in TGFβ1 expression or its signaling in T cells...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805009/ https://ncbi.nlm.nih.gov/pubmed/17977791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2007.08.005 |
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