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Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis

The synthesis of novel fluorogenic retro-aldol substrates for aldolase antibody 38C2 is described. These substrates are efficiently and specifically processed by antibody aldolases but not by natural cellular enzymes. Together, the fluorogenic substrates and antibody aldolases provide reporter gene...

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Main Authors: List, Benjamin, Barbas, Carlos F., Lerner, Richard A.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC28046/
https://ncbi.nlm.nih.gov/pubmed/9860972
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