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Aminoquinoline Surfen Inhibits the Action of SEVI (Semen-derived Enhancer of Viral Infection)

In semen, proteolytic peptide fragments from prostatic acid phosphatase can form amyloid fibrils termed SEVI (semen-derived enhancer of viral infection). These fibrils greatly enhance human immunodeficiency virus (HIV) infectivity by increasing the attachment of virions to target cells. Therefore, S...

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Détails bibliographiques
Auteurs principaux: Roan, Nadia R., Sowinski, Stefanie, Münch, Jan, Kirchhoff, Frank, Greene, Warner C.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804344/
https://ncbi.nlm.nih.gov/pubmed/19897482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066167
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