The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeficiency Virus Infection

Human semen contains peptides capable of forming amyloid fibrils termed semen-derived enhancer of viral infection (SEVI) that can greatly increase human immunodeficiency virus (HIV) infection. While SEVI appears to enhance virion attachment to target cells, its underlying mechanism of action is unkn...

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Detalhes bibliográficos
Main Authors: Roan, Nadia R., Münch, Jan, Arhel, Nathalie, Mothes, Walther, Neidleman, Jason, Kobayashi, Akiko, Smith-McCune, Karen, Kirchhoff, Frank, Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612336/
https://ncbi.nlm.nih.gov/pubmed/18945786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01366-08
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