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Quantifying uncertainty in genotype calls

Motivation: Genome-wide association studies (GWAS) are used to discover genes underlying complex, heritable disorders for which less powerful study designs have failed in the past. The number of GWAS has skyrocketed recently with findings reported in top journals and the mainstream media. Microarray...

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Bibliographic Details
Main Authors: Carvalho, Benilton S., Louis, Thomas A., Irizarry, Rafael A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804295/
https://ncbi.nlm.nih.gov/pubmed/19906825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp624
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