A carregar...
Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography
Structural studies are part of a rational drug design program aimed at inhibiting the S100B–p53 interaction and restoring wild-type p53 function in malignant melanoma. To this end, structures of three compounds (SBi132, SBi1279, and SBi523) bound to Ca(2+)-S100B were determined by X-ray crystallogra...
Na minha lista:
| Main Authors: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804263/ https://ncbi.nlm.nih.gov/pubmed/19469484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9005754 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|