Translocation of Sphingosine Kinase 1 to the Plasma Membrane Is Mediated by Calcium- and Integrin-binding Protein 1

SK1 (sphingosine kinase 1) plays an important role in many aspects of cellular regulation. Most notably, elevated cellular SK1 activity leads to increased cell proliferation, protection from apoptosis, and induction of neoplastic transformation. We have previously shown that translocation of SK1 fro...

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Bibliographic Details
Main Authors: Jarman, Kate E., Moretti, Paul A. B., Zebol, Julia R., Pitson, Stuart M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804196/
https://ncbi.nlm.nih.gov/pubmed/19854831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068395
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