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Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

Sphingosine kinase 1 is an agonist-activated signalling enzyme that catalyses the formation of sphingosine 1-phosphate, a lipid second messenger that has been implicated in a number of agonist-driven cellular responses, including stimulation of cell proliferation, inhibition of apoptosis and express...

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Detalhes bibliográficos
Main Authors: Pitson, Stuart M., Moretti, Paul A.B., Zebol, Julia R., Lynn, Helen E., Xia, Pu, Vadas, Mathew A., Wattenberg, Binks W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213794/
https://ncbi.nlm.nih.gov/pubmed/14532121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg540
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