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Eukaryotic Elongation Factor 1A Interacts with Sphingosine Kinase and Directly Enhances Its Catalytic Activity

Sphingosine 1-phosphate (S1P) has many important roles in mammalian cells, including contributing to the control of cell survival and proliferation. S1P is generated by sphingosine kinases (SKs), of which two mammalian isoforms have been identified (SK1 and SK2). To gain a better understanding of SK...

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Detalhes bibliográficos
Main Authors: Leclercq, Tamara M., Moretti, Paul A. B., Vadas, Mathew A., Pitson, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442288/
https://ncbi.nlm.nih.gov/pubmed/18263879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708782200
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