ASXL1 Represses Retinoic Acid Receptor-mediated Transcription through Associating with HP1 and LSD1

We previously suggested that ASXL1 (additional sex comb-like 1) functions as either a coactivator or corepressor for the retinoid receptors retinoic acid receptor (RAR) and retinoid X receptor in a cell type-specific manner. Here, we provide clues toward the mechanism underlying ASXL1-mediated repre...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Sang-Wang, Cho, Yang-Sook, Na, Jung-Min, Park, Ui-Hyun, Kang, Myengmo, Kim, Eun-Joo, Um, Soo-Jong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Transcription, Chromatin, and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804164/
https://ncbi.nlm.nih.gov/pubmed/19880879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065862
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