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CACUL1 reciprocally regulates SIRT1 and LSD1 to repress PPARγ and inhibit adipogenesis

Peroxisome proliferator-activated receptor γ (PPARγ) is the master regulator of adipocyte differentiation and is closely linked to the development of obesity. Despite great progress in elucidating the transcriptional network of PPARγ, epigenetic regulation of this pathway by histone modification rem...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jang, Min Jun, Park, Ui-Hyun, Kim, Jeong Woo, Choi, Hanbyeul, Um, Soo-Jong, Kim, Eun-Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870580/
https://ncbi.nlm.nih.gov/pubmed/29233982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0070-z
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