Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells

Human sirtuin 1 (SIRT1) is a NAD(+)-dependent deacetylase that participates in cell death/survival, senescence and metabolism. Although its substrates are well characterized, no direct regulators have been defined. Here, we show that SIRT1 associates with SKI-interacting protein (SKIP) and modulates...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kang, Moo-Rim, Lee, Sang-Wang, Um, Elisa, Kang, Hyun Tae, Hwang, Eun Seong, Kim, Eun-Joo, Um, Soo-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817470/
https://ncbi.nlm.nih.gov/pubmed/19934264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados